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Diflucan (Fluconazole)
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Fluconazole (Diflucan)
Single-dose therapy for vaginal yeast infection revolutionized outpatient management.
Diflucan (Fluconazole)
Diflucan is often used for esophageal candidiasis in immunocompromised hosts.
Diflucan (Fluconazole)
A paradigm for how a single molecule can transform the management of a wide range of fungal diseases.
Fluconazole (Diflucan)
Diflucan is ineffective against Candida auris, a major multidrug-resistant pathogen.
Diflucan (Fluconazole)
For oropharyngeal thrush, Diflucan is often more effective than topical nystatin.
Fluconazole
Headache and gastrointestinal disturbances are the most frequently reported adverse events.
Fluconazole (Diflucan)
Fungicidal activity is observed only at very high concentrations against some species.
Diflucan (Fluconazole)
Diflucan may interact with calcium channel blockers, potentiating effects.
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Diflucan (Fluconazole)
Its success spurred the development of broader-spectrum triazoles like voriconazole and posaconazole.
Diflucan
Diflucan is used for chronic suppression in patients with recurrent mucosal infections.
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Diflucan has a well-established role in treating fungal keratitis caused by susceptible yeasts.
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Fluconazole (Diflucan)
Diflucan is often used in pediatric antifungal therapy with weight-based dosing.
Diflucan
Diflucan exhibits fungistatic, not fungicidal, activity against most susceptible yeasts.
Fluconazole (Diflucan)
Diflucan may be used for step-down therapy after initial echinocandin treatment for candidemia.
Diflucan
Diflucan can cause a severe cutaneous reaction like Stevens-Johnson syndrome.
Diflucan
Excellent CSF penetration makes it a mainstay for cryptococcal meningitis suppression.
Diflucan
Teratogenicity concerns (Category D) limit its use in pregnancy, especially first trimester.
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Diflucan
Activity against dermatophytes underpins its use in extensive tinea infections.
Diflucan (Fluconazole)
Represents a critical tool whose utility is now carefully balanced against the rising tide of antifungal resistance.
Diflucan
«Fluconazole-refractory» candidiasis is a specific clinical entity in advanced AIDS.
Diflucan (Fluconazole)
Therapeutic drug monitoring is not routinely required but can be useful in specific scenarios.
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Diflucan (Fluconazole)
Diflucan is a critical component of induction-consolidation-maintenance strategies for cryptococcosis.
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Fluconazole (Diflucan)
Diflucan can lead to clinically significant interactions with immunosuppressants like tacrolimus.
Diflucan (Fluconazole)
Diflucan has reliable activity against Coccidioides immitis for certain non-meningeal cases.
Fluconazole
Diflucan penetration into the CSF is excellent, a key pharmacological advantage.
Fluconazole (Diflucan)
Diflucan can be used for prolonged periods in certain endemic mycoses.
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Fluconazole (Diflucan)
Diflucan has activity against many dermatophytes, supporting its use in tinea infections.
Diflucan (Fluconazole)
The «trailing effect» in Diflucan susceptibility testing can complicate interpretation.
Fluconazole (Diflucan)
Its chemical stability contributes to a long shelf life and easy formulation.
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Diflucan (Fluconazole)
Diflucan is a standard part of the workup for a patient with suspected invasive fungal infection.
Diflucan
Administered perioperatively in some surgical prophylaxis guidelines for high-risk patients.
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Diflucan
Intrinsically resistant organisms include Candida krusei and the Mucorales order.
Fluconazole
Diflucan may deplete coenzyme Q10 with long-term use, a theoretical concern.