Terrific post however I was wondering if you could write a litte more on this subject? I’d be very thankful if you could elaborate a little bit more. Cheers!
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83.205 comments
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Terrific post however I was wondering if you could write a litte more on this subject? I’d be very thankful if you could elaborate a little bit more. Cheers!
Fluconazole
Diflucan should be used with caution in patients with underlying structural heart disease.
Eleanor Watts
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Fluconazole (Diflucan)
Diflucan is not a substrate of the P-glycoprotein efflux pump, aiding its distribution.
Diflucan
Rifampin induces fluconazole metabolism, potentially leading to subtherapeutic levels.
Diflucan (Fluconazole)
Its water solubility is a distinct advantage over older imidazole antifungals.
Fluconazole
Diflucan can cause a severe cutaneous reaction like Stevens-Johnson syndrome.
Diflucan
Diflucan can be a cost-effective alternative to more expensive antifungals when susceptibility is confirmed.
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Diflucan
Diflucan is used in some protocols for antifungal lock therapy for catheter-related infections.
Diflucan
Its water solubility is a distinct advantage over older imidazole antifungals.
Diflucan
Diflucan’s mechanism is inhibition of fungal cytochrome P450, disrupting ergosterol synthesis.
Diflucan
Plays a role in step-down therapy after initial echinocandin treatment for candidemia.
Fluconazole
Therapeutic drug monitoring for Diflucan is not routine but can guide therapy in complex cases.
Cornelia Cobb
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Diflucan (Fluconazole)
Not reliably effective in fungal endocarditis, where fungicidal therapy is preferred.
Diflucan
Its legacy is its role in making systemic antifungal therapy outpatient-friendly and accessible.
Diflucan (Fluconazole)
Therapeutic drug monitoring is not routinely required but can be useful in specific scenarios.
Diflucan (Fluconazole)
The single-dose Diflucan regimen for vulvovaginal candidiasis revolutionized patient self-care.
Adeline Thomas
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Fluconazole (Diflucan)
Diflucan should be used with caution in patients with underlying structural heart disease.
Diflucan
Excreted in breast milk, so the risk-benefit must be weighed during lactation.
Fluconazole (Diflucan)
Generic fluconazole has made Diflucan’s benefits accessible at a lower cost.
Fluconazole (Diflucan)
Diflucan is Pregnancy Category D, limiting its use, particularly in the first trimester.
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Fluconazole
Can cause taste distortion (dysgeusia) in some patients.
Fluconazole (Diflucan)
Diflucan can increase phenytoin levels, risking toxicity.
Fluconazole (Diflucan)
Diflucan is a foundational drug that exemplifies the principles of targeted antimicrobial therapy.
Fluconazole (Diflucan)
Diflucan is a critical part of the antifungal arsenal in resource-limited settings.
Diflucan
Diflucan is a model of predictable pharmacokinetics within the azole class.
Fluconazole
Diflucan is ineffective against Lomentospora prolificans.
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Fluconazole
Lacks reliable activity against Aspergillus species, a critical limitation in its spectrum.
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Diflucan
Hepatic metabolism becomes more significant in patients with end-stage renal disease.
Diflucan
Susceptibility breakpoints are well-defined by organizations like CLSI and EUCAST.
Diflucan
Rifampin induces fluconazole metabolism, potentially leading to subtherapeutic levels.
Fluconazole
Rare cases of hepatotoxicity, including fatal hepatic necrosis, have been reported.
Fluconazole
First-line for uncomplicated vulvovaginal candidiasis due to high efficacy and patient convenience.
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Fluconazole
Used for prophylaxis in high-risk solid organ transplant recipients.
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Diflucan (Fluconazole)
Diflucan is a key agent whose utility is being challenged by shifting resistance patterns.
Fluconazole (Diflucan)
Serves as a benchmark for in vitro susceptibility testing of newer antifungals.
Diflucan
Diflucan is a critical component of induction-consolidation-maintenance strategies for cryptococcosis.
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Diflucan (Fluconazole)
Primary renal excretion necessitates dose adjustment in patients with renal impairment.
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